All functions |
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Set CAMDAC configuration |
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Build CAMDAC sample object |
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LogR_correction |
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Assign copy number calls |
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ascat.m.plotRawData |
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ascat.m.plotSegmentedData |
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Run allele-specific methylation analysis pipeline |
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Manually assign output file to CAMDAC sample |
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Cluster CpGs into annotated bins |
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Bind SNPs |
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Call CNA |
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Call tumour-normal DMPs |
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Call tumour-normal DMRs |
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Count alleles |
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Deconvolve methylation |
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Make methylation |
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Make SNPs |
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Run ASCAT.m |
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Run battenberg |
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Compute the tumour methylation rate |
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Count alleles for reads phased to SNPs in a BAM file |
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Download CAMDAC pipeline files |
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Format methylation rates |
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Format output nucleotide counts |
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Get DMPs |
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Assign bins |
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Compile allele counts at SNPs and at CpGs for bisulfite sequencing data |
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Perform differential methylation analysis on deconvolute tumour methylation rates |
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get_msp1_fragments |
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Deconvolve the pure tumour methylation rate from bisulfite sequencing data |
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Get CAMDAC reference files from config |
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@param ICDFname is R's name for the inverse cumulative density function of the distribution. |
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Parse ASCAT and bb output directories to load CNA data |
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Load allele count files |
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Panel ASM from counts Basic function to create an ASM methylation panel from allele count or ASM meth files WARNING: In active development. |
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Make CAMDAC methylation panel from a matrix of beta values |
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Make CAMDAC methylation panel from allele counts Methylation fractions are obtained by summing M and UM reads across samples |
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CAMDAC tumor-normal pipeline |
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Call CAMDAC for a tumor and patient-matched normal sample |
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Plot BAF and logR profiles with ggplot |
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Plot SNP data summary and QC |
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Plot Methylation |
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Plot plots SNP QC |
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Preprocess a list of CamSample objects for analysis |
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Preprocess a list of CamSample objects for ASM analysis |
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remove_low_cov_singletons |
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Obtain allele-specific copy number profiles, tumour purity and plot SNP data |
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Filter bulk tumour and normal methylation data, get methylation rate highest density interval (HDI) and plot raw methylation info |
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Sort a data table with genomic coordinates |